In a sentence: Atletico Madrid travel to El Madrigal with their heads held high after thumping Lokomotiv Moscow 5-1 in Russia on Thursday, and how that trip will affect their squad for a tough tie against Villarreal is one of the main questions in our La Liga preview as both sides are enjoying impressive seasons.
Last time: It was a surprisingly comfortable three-points for the Yellow Submarine the last time Atleti came to town. During their 2016 La Liga contest, two first-half goals coupled with a 93rd minute Roberto Soriano strike gave the hosts a 3-0 victory
This time: Villarreal are 16/5 with Atletico Madrid at 21/20 and the draw 21/10
You might remember: Who can forget that high octane 4-4 draw during a 2008 La Liga match? Razl Garcia equalised in the 85th minute to snatch a point for Atleti in a match that was described by Spanish press as ‘Madness’.