The Las Vegas Raiders enter Week 5 with a
3-1 record
and a stronger statistical profile than the 2-2 New England Patriots. The key betting angle is the Raiders' offense, which averages
28.8 points per game, while Kirk Cousins has thrown for 1,026 yards and 11 touchdowns through four games.
The Patriots are
favored by 3.5 points
at DraftKings, with a
moneyline of -192
and a
total of 45.5. New England has home-field advantage, but its -5 turnover differential and 16.2 points per game create a clear gap in the numbers behind these NFL Picks.
Raiders vs Patriots Game Preview
Las Vegas is 3-1 and has covered in all four games this season, while New England is 2-2 and has gone 2-1 against the spread over its last three. Cousins owns a 99.48 passer rating with 7.13 yards per attempt, 11 touchdowns and four interceptions, while Drake Maye has 854 passing yards, four touchdowns and seven interceptions with a 70.96 rating. Those numbers support the Raiders in this matchup and are central to the NFL predictions here.
The injury report also favors Las Vegas. Raiders center Jackson Powers-Johnson is out with a groin injury, while Aidan O'Connell is questionable and Ashton Jeanty and Brock Bowers are dealing with minor injuries. New England has Christian Gonzalez, Christian Barmore, Channing Canada and Brenden Schooler listed out, while the Raiders also arrive after a cross-country trip for a 1 p.m. ET kickoff.
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Raiders vs Patriots Moneyline Pick
Take the
Las Vegas Raiders moneyline at +160 at DraftKings. Las Vegas ranks eighth in the NFL at 28.8 points per game and fourth with a +3 turnover differential, while New England ranks 30th at 16.2 points per game and 27th at -5 in turnover differential.
The +160 price also gives the Raiders enough upside to offset the road setting. Cousins has 11 touchdown passes against four interceptions, while Maye has seven interceptions through four games, making the Raiders the better price based on current offensive production.
Pick: Raiders ML (+160 at DraftKings).
Against the Spread Pick
Take
Las Vegas Raiders +3.5 at -110 at DraftKings. The Raiders are 4-0 against the spread this season and have covered as underdogs of +3.5 or more in their recent road wins at the Los Angeles Chargers and New Orleans Saints.
The key number is 3.5, which gives Las Vegas protection against a field-goal win by New England. The Raiders also have a 28.8-point scoring average compared with 16.2 for the Patriots, so a three-point game fits the current Trends in NFL team performance better than a New England win by a full touchdown. Bettors should compare this number through a sports betting app before wagering.
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Raiders vs Patriots Game Total Pick
Take the
Under 45.5 at -115 at DraftKings. New England averages only 16.2 points per game and has scored 46 points across its last two games, while the Raiders' defense has recorded 12 sacks and four interceptions through four games.
The Patriots' offensive efficiency is the main concern for the Over, while the Raiders' defense has enough pressure to limit Maye's passing game. The 64°F forecast in Foxborough also provides neutral conditions, leaving the Under dependent mainly on New England's scoring output rather than weather.
Pick: Under 45.5 (-115 at DraftKings).
How to Watch Raiders vs Patriots and Game Info
- Location:
Gillette Stadium, Foxborough, MA
- Date:
Sunday, October 11, 2026
- Kickoff:
1:00 p.m. ET
- TV:
CBS
- Las Vegas Raiders starting quarterback:
Kirk Cousins (3-1, 1,026 yards, 11-4).
- New England Patriots starting quarterback:
Drake Maye (2-2, 854 yards, 4-7).
- Weather forecast:
64°F, cloudy throughout the afternoon, and wind at approximately 12 to 13 mph.
Final Takeaways
The Raiders are the better betting side despite playing on the road, with a 28.8-point scoring average, 4-0 ATS record and +3 turnover differential. The NFL Picks are Las Vegas on the moneyline at +160 and Raiders +3.5 at -110, while the game total is Under 45.5 at -115. These NFL predictions lean on the Raiders' stronger offense and turnover profile, while the Trends in NFL team performance point to a close game with limited scoring from New England.
All odds as of 4:51 a.m. ET on October 6, 2026. Odds sourced from DraftKings Sportsbook. Check the latest odds and line movement for
Las Vegas Raiders vs New England Patriots
at betting.net before placing your bets.
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