Saints Vs Giants: Betting Picks and Odds for NFL Week 6 Matchup
Jesse M. Cox Published 15/10/2026
The New York Giants are the preferred side against the New Orleans Saints in Sunday's Week 6 matchup. DraftKings lists New York at -102 on the moneyline, while New Orleans is -115 despite a three-game losing streak and a defense allowing 30.2 points per game. These NFL predictions favor the Giants, who have a strong home record against the spread.
The Giants are 3-0 ATS at home, whereas New Orleans has failed to cover in both games as a favorite of 1.5 points or more. Our NFL Picks back New York to win outright, cover +1.5, and keep the game Under 45.5 points. Bettors should focus on the turnover gap and New Orleans' defensive problems when weighing these markets.
Saints vs Giants Game Preview
New Orleans enters Week 6 at 1-4 after three straight losses, averaging 23.6 points and 322 yards per game. Tyler Shough has thrown for 1,299 yards, nine touchdowns, and five interceptions, while the Giants are 3-1-1 and average 21.8 points on 308.2 yards per game. Jameis Winston has recorded 805 passing yards, six touchdowns, and three interceptions for New York.
The Giants' offensive line has concerns, with Andrew Thomas and Jermaine Eluemunor missing practice, while Abdul Carter is also sidelined. Saints WR Chris Olave missed practice, and RB Travis Etienne Jr. is on injured reserve. MetLife Stadium is forecast to be sunny at 58°F, with west-southwest winds of 5–6 mph. These factors shape the NFL predictions.
Saints vs Giants Moneyline Pick
Take the New York Giants moneyline at -102 at DraftKings. New York has a stronger turnover profile, with six interceptions and a +1 turnover differential compared with New Orleans' one interception and -6 differential. Those numbers give the Giants a clear path to winning a close game.
The -102 price is reasonable for a home underdog with a 3-1-1 record. New Orleans has lost three straight and allowed 30.2 points per game, making the Saints difficult to trust as slight road favorites. These NFL Picks favor New York to take advantage of the Saints' recent defensive struggles.
Pick: New York Giants ML (-102 at DraftKings).
Against the Spread Pick
Take the New York Giants +1.5 at +100 at DraftKings. The Giants have covered the spread in all three home games this season, while the Saints are 0-2 ATS as favorites of at least 1.5 points. That trend supports backing New York to keep the game close or pull off an upset.
Taking the Giants and the points offers some cushion in a tight matchup. New Orleans averages 23.6 points per game but has lost three straight and allows 30.2 points per game. These NFL predictions favor New York to cover the spread.
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Pick: New York Giants +1.5 (+100 at DraftKings).
Saints vs Giants Game Total Pick
Take the Under 45.5 points. New Orleans averages 23.6 points per game, and New York averages 21.8, giving the teams a combined average of 45.4 points. That is just below the posted total, leaving little room for either offense to fall short of expectations and still push the game Over.
Olave's missed practice adds uncertainty to a Saints offense that needs its receiver to produce. The Giants have also recorded six interceptions, while New Orleans has a -6 turnover differential. This statistical analysis of NFL teams supports the Under if turnovers and stalled drives limit scoring opportunities. The total price from DraftKings was not supplied, so bettors should confirm the available odds before placing a wager.
Pick: Under 45.5 (odds TBD at DraftKings).
How to Watch New Orleans Saints vs New York Giants and Game Info
- Location: MetLife Stadium, East Rutherford, New Jersey.
- Date: Sunday, October 18, 2026
- Kickoff: 1:00 p.m. ET
- TV: FOX
- New Orleans Saints starting quarterback: Tyler Shough (record as starter: TBD, 1,299 passing yards, 9-5 TD-INT).
- New York Giants starting quarterback: Jameis Winston (record as starter: TBD, 805 passing yards, 6-3 TD-INT).
- Weather forecast: 58°F, sunny, west-southwest winds at 5-6 mph.
Final Takeaways
The Giants offer value against a Saints team on a three-game losing streak that allows 30.2 points per game. Our NFL Picks are Giants ML (-102), Giants +1.5 (+100), and Under 45.5, pending total odds confirmation. These picks lean toward New York based on its 3-0 home ATS record and the turnover gap, while statistical analysis points to a close game.
All odds as of TBD ET on October 15, 2026. Odds sourced from DraftKings. Check the latest odds and line movement for New Orleans Saints vs New York Giants at betting.net before placing your bets.