Cowboys at Texans Predictions, Odds and Betting Picks
The Houston Texans are 2.5-point home favorites over the Dallas Cowboys, with FanDuel listing Houston at -136 on the moneyline and the total at 47.5. Dallas enters with 730 passing yards and 7 touchdowns from Dak Prescott, while Houston has 11 sacks through three games.
The biggest betting factor is the matchup between Houston's pass rush and a Dallas defense that has only 2 sacks and 0 interceptions. With the Texans also expecting Nico Collins back from a hamstring issue and Dallas missing key defensive backs, these NFL Picks lean toward Houston on the moneyline, Dallas with the points, and an Over 47.5 total.
Cowboys vs Texans Game Preview
Dallas is 1-2 through three games and has covered twice, while Houston is 0-3 against the spread. Prescott has completed 69.5% of his passes for 730 yards, 7 touchdowns and 1 interception, while C.J. Stroud has 794 yards, 3 touchdowns and no interceptions on 60% passing.
The injury report gives both offenses and defenses important variables. Dallas has lost Jalen Thompson and P.J. Locke to injured reserve, while Cobie Durant is listed as a major concern and Malik Hooker has returned to practice. Houston has Nico Collins and Ed Ingram practicing on a limited basis, while Azeez Al-Shaair has missed practice and Will Anderson Jr. and Jadeveon Clowney have participated. NRG Stadium is expected to provide a controlled indoor setting despite Houston's forecast for light rain and 81-degree conditions outside.
Cowboys vs Texans Moneyline Pick
Take the Houston Texans ML at -136 at FanDuel Sportsbook. Houston's 11 sacks are third in the league, and Will Anderson Jr. already has 4 sacks and 7 quarterback pressures. That pressure advantage matters against Dallas because the Cowboys have allowed Stroud's defense to generate 10 sacks while producing only 2 of their own.
The price is fair for a home favorite with a 60.8% numberFire win probability and a healthier pass rush. Houston's defense also has a +1 turnover differential compared with Dallas at 0, while Dallas has yet to record an interception. These NFL predictions favor the Texans to control enough key downs to win outright.
Pick: Houston Texans ML (-136 at FanDuel Sportsbook).
Against the Spread Pick
Take Dallas Cowboys +2.5 at -110 at FanDuel Sportsbook. Dallas has covered twice in three games and is 1-0 against the spread when catching at least 2.5 points this season. The Cowboys also average 29.3 points per game, compared with only 18.0 for Houston, giving Dallas enough scoring power to stay within one possession.
The 2.5-point number sits just below the key number of 3, which gives Dallas useful protection in a game projected to stay close. Prescott has thrown 7 touchdowns against only 1 interception, while CeeDee Lamb has 309 receiving yards and 3 touchdowns. That passing production creates a strong backdoor-cover threat if Houston leads late.
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Pick: Dallas Cowboys +2.5 (-110 at FanDuel Sportsbook).
Cowboys vs Texans Game Total Pick
Take the Over 47.5 at -110 at FanDuel Sportsbook. Dallas is averaging 29.3 points per game and 330.3 yards, while Houston has produced 326 yards per game despite averaging only 18 points. Dallas has also allowed 10 or more sacks? No, Houston has recorded 11 sacks, which creates turnover and short-field chances that can help push the total higher.
The Cowboys' depleted secondary adds another reason to expect points. Houston has 794 passing yards through three games, and Collins has returned to practice after missing the previous two weeks. With the game expected to be played under a closed NRG Stadium roof, outdoor rain and humidity should not slow the passing attacks.
Pick: Over 47.5 (-110 at FanDuel Sportsbook).
How to Watch Dallas Cowboys vs Houston Texans and Game Info
- Location: NRG Stadium, Houston, TX.
- Date: Sunday, October 4, 2026
- Kickoff: 1:00 p.m. ET
- TV: FOX
- Dallas Cowboys starting quarterback: Dak Prescott (TBD, 730 yards, 7-1).
- Houston Texans starting quarterback: C.J. Stroud (TBD, 794 yards, 3-0).
- Weather forecast: Indoors, no weather factor.
Final Takeaways
Houston has the stronger moneyline case with 11 sacks to Dallas' 2, but Dallas can cover +2.5 behind Prescott's 7-1 TD-INT mark and Lamb's 309 yards. NFL Picks are Texans ML, Cowboys +2.5 and Over 47.5, while NFL predictions point to a close, high-scoring game. Statistical analysis of NFL teams also supports the Over, with Dallas averaging 29.3 points against Houston's depleted secondary.
All odds as of 1:08 AM ET on October 1, 2026. Odds sourced from FanDuel Sportsbook. Check the latest odds and line movement for Dallas Cowboys vs Houston Texans at betting.net before placing your bets.