Cardinals Vs Cowboys: Betting Picks and Odds for NFL Week 8 Matchup
David Genge Published 28/10/2026
The Dallas Cowboys are 6.5-point home favorites against the Arizona Cardinals in their Week 8 matchup on Sunday, November 1. DraftKings lists Dallas at -280 on the moneyline, with the spread at -6.5 (-104) and the game total at 53.5 points (Over -113, Under +106). These NFL Picks favor Dallas to win and cover, while the Over depends on Arizona contributing enough points to support the high total.
The Cowboys scored 38 points in its latest reported win over Philadelphia and averages 27 points per game, ranking fifth in the NFL. Arizona averages 20.3 points per game and enters the matchup with injury concerns involving safety Budda Baker and running back Jeremiyah Love. These NFL predictions center on Dallas' stronger passing production and the potential for both teams to contribute to a high-scoring game.
Cardinals vs Cowboys Game Preview
Dallas quarterback Dak Prescott has recorded 1,851 passing yards, 13 touchdowns and five interceptions in the supplied team leaders data. Arizona quarterback Jacoby Brissett has 1,600 passing yards, 10 touchdowns and six interceptions. Dallas also averages 353.6 total yards per game, compared with Arizona's 313.9, giving the Cowboys an advantage in overall offensive production.
Arizona listed Baker, Love, Andrew Wingard, Walter Nolen III, Carson Beck and Max Melton as not practicing in the supplied injury report. Dallas listed Drew Shelton and Dee Winters as out, while KaVontae Turpin was questionable with a rib injury. The game will take place at AT&T Stadium in Arlington, Texas, where the retractable roof and climate control mean weather should not affect playing conditions.
Cardinals vs Cowboys Moneyline Pick
The Dallas Cowboys moneyline at -280 is the pick. Prescott has thrown 13 touchdowns against five interceptions, while wide receiver CeeDee Lamb has recorded 651 receiving yards and six touchdowns. Dallas also averages 27 points per game, giving the home team a stronger offensive profile than Arizona's 20.3-point average.
ESPN Analytics gives Dallas a 76.1% chance to win, according to the supplied matchup information. That projection supports the Cowboys, although bettors must weigh the return on a -280 price before placing a wager. Comparing the best NFL betting sites can help bettors assess the available markets and sportsbook options.
Pick: Dallas Cowboys ML (-280 at DraftKings).
Against the Spread Pick
Take Dallas Cowboys -6.5 at -104. Dallas averages 27 points per game, while Arizona averages 20.3, creating a 6.7-point gap between their scoring averages. That difference puts the Cowboys in position to cover the spread if both teams perform near their usual offensive levels.
The Cowboys scored 38 points against Philadelphia in its previous reported game, showing its ability to build a lead. Arizona has recorded 15 defensive sacks, ranking 19th, while Dallas has 10, ranking 27th, according to the supplied statistics. The Cowboys' negative turnover differential of -3 remains a concern, but Arizona's reported injuries add uncertainty to its ability to keep the game within one score.
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Pick: Dallas Cowboys -6.5 (-104 at DraftKings).
Cardinals vs Cowboys Game Total Pick
Take the Over 53.5 points at -113. Dallas averages 27 points per game, and its 38-point performance against Philadelphia provides evidence of its scoring potential. However, Arizona averages only 20.3 points, leaving the combined average at 47.3 and requiring both offenses to exceed that baseline to clear the total.
Prescott's 13 passing touchdowns and Lamb's six receiving touchdowns give Dallas two proven sources of scoring production in the supplied statistics. Brissett has thrown 10 touchdowns and six interceptions, a combination that offers Arizona scoring potential but also creates turnover risk. With the game being played indoors at AT&T Stadium, weather is not expected to disrupt offensive execution.
Pick: Over 53.5 (-113 at DraftKings).
How to Watch Arizona Cardinals vs Dallas Cowboys and Game Info
- Location: AT&T Stadium, Arlington, Texas.
- Date: Sunday, November 1, 2026
- Kickoff: 1:00 p.m. ET
- TV: FOX
- Arizona Cardinals starting quarterback: Jacoby Brissett (record as starter: TBD, 1,600 yards, 10-6 TD-INT).
- Dallas Cowboys starting quarterback: Dak Prescott (record as starter: TBD, 1,851 yards, 13-5 TD-INT).
- Weather forecast: Indoors, no weather factor.
Final Takeaways
The Dallas Cowboys has the advantage in passing production, scoring average and home-field conditions, making the Cowboys the leading choice in these NFL Picks. The recommended NFL predictions are Dallas on the moneyline at -280 and Dallas -6.5 at -104, both at DraftKings. The Over 53.5 at -113 is the total pick, though Arizona's 20.3-point scoring average means the Over needs more production from the Cardinals than their season average suggests. These Expert betting tips for NFL games focus on Dallas' offensive edge while accounting for the risks attached to the spread and total.
All odds as of 1:37 a.m. ET on October 28, 2026. Odds sourced from DraftKings. Check the latest odds and line movement for Arizona Cardinals vs Dallas Cowboys at betting.net before placing your bets.