The Chicago Bears host the New England Patriots on Thursday, October 22, in a Week 7 matchup with three clear betting angles. DraftKings Sportsbook lists Chicago at
-165 on the moneyline, the
Patriots at +135, and the Bears as
three-point favorites. The game total is 50 points, putting the focus on Chicago's control of possession and New England's turnover problems. Moneyline odds are expressed in American odds format, with wagers placed in US dollars (USD).
Chicago averages 36:01 in time of possession per game, the best mark in the league in the supplied statistics. New England has a -6 turnover differential, ranked 30th, compared with Chicago's -2 mark. These NFL predictions favor the home team to win, but the spread and total offer separate opportunities for bettors.
Patriots vs Bears Game Preview
New England averages 22.7 points and 374.2 yards per game, while Chicago posts 25 points and 388.3 yards. Drake Maye has 1,463 passing yards, 11 touchdowns and seven interceptions, compared with Caleb Williams' 712 yards, three touchdowns and one interception. These stats shape the NFL predictions, with Maye's turnovers a key concern.
Both teams face injury concerns on a short turnaround. Ben Brown, Alijah Vera-Tucker and Carlton Davis III missed New England's walkthrough, while Romeo Doubs is on injured reserve. Chicago's Jonah Jackson is week-to-week, and T.J. Edwards and Jack Sanborn also missed practice. Kickoff is 8:15 p.m. ET at Soldier Field, where temperatures in the 50s and lakefront winds could influence these NFL Picks.
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Patriots vs Bears Moneyline Pick
Take the Chicago Bears moneyline at -165.
Chicago has a strong possession advantage, averaging 36:01 per game, and its defense has recorded 17 sacks compared with New England's 14. Playing at Soldier Field gives the Bears another advantage in a matchup where their defense can pressure Maye and force difficult decisions.
Chicago's offense averages 25 points per game, and its -2 turnover differential is better than New England's -6. At -165 American odds, a $165 wager would return $100 in profit if the Bears win, plus the original $165 stake. These NFL Picks favor Chicago for its stronger turnover profile and possession control.
Pick: Chicago Bears ML (-165 at DraftKings Sportsbook).
Against the Spread Pick
Take the New England Patriots +3.
The three-point spread is a key NFL betting number because a Patriots loss by exactly three points would result in a push. New England averages 374.2 yards per game, giving Maye's offense a reasonable path to keep the score close even if Chicago controls possession.
The Patriots also average 31:17 in time of possession, ranking 11th in the supplied figures. That gives them a foundation for sustaining drives and limiting the number of possessions available to Chicago. The Bears' 17 sacks remain a threat, but the three-point cushion makes New England the spread pick.
Pick: New England Patriots +3 (odds TBD at DraftKings Sportsbook).
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Patriots vs Bears Game Total Pick
Take the Over 50 points.
Chicago averages 25 points per game, and New England averages 22.7, giving the teams a combined average of 47.7 points. The Over needs at least 51 points to cash, so both offenses must perform above their combined average.
Chicago averages 388.3 yards per game, while New England adds 374.2. Maye's 11 touchdown passes support the scoring case, though his seven interceptions add risk. These expert betting tips for NFL games favor the Over, but confirm the total and odds before betting.
Pick: Over 50 (odds TBD at DraftKings Sportsbook).
How to Watch Patriots vs Bears and Game Info
- Location:
Soldier Field, Chicago, Illinois.
- Date:
Thursday, October 22, 2026
- Kickoff:
8:15 p.m. ET
- TV:
Amazon Prime Video
- New England Patriots starting quarterback:
Drake Maye (record as starter: TBD, 1,463 passing yards, 11 TD, 7 INT).
- Chicago Bears starting quarterback:
Caleb Williams (record as starter: TBD, 712 passing yards, 3 TD, 1 INT).
- Weather forecast:
Temperatures in the 50s°F, typical fall conditions, wind direction and speed TBD.
Final Takeaways
Chicago is the moneyline pick at -165, backed by its possession advantage and better turnover differential. New England +3 is the spread pick, as the Patriots average 374.2 yards per game and can keep the game close. The Over 50 is the total pick, with both teams averaging 47.7 combined points. These NFL predictions and NFL Picks reflect the supplied stats. Confirm current odds and injury updates before betting.
Check the latest odds and line movement for
Patriots vs. Bears at betting.net
before placing your bets. All odds as of TBD ET on October 20, 2026. Odds sourced from DraftKings Sportsbook. All monetary amounts are in US dollars (USD).
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