Seahawks Vs Raiders: Betting Picks and Odds for NFL Week 10 Matchup
David Genge Published 13/11/2026
The Seattle Seahawks travel to face the Las Vegas Raiders on Sunday, November 15, with DraftKings making Seattle a 6.5-point road favorite. Las Vegas will start rookie quarterback Fernando Mendoza after trading Kirk Cousins to Minnesota, while Seattle will be without Sam Darnold for a second straight game. The quarterback changes are central to the betting outlook, especially with Mendoza preparing for his first NFL start.
Seattle enters Week 10 with a 5-4 record and a defense allowing just 18.0 points per game. Las Vegas is 4-5 and averages 26.4 points, but its rushing attack ranks last in the league at 71.3 yards per game. These NFL Picks focus on Seattle's defensive advantage, the Raiders' inexperienced quarterback and the potential for a lower-scoring matchup.
Seahawks vs Raiders Game Preview
The Seahawks average 22.4 points per game, with Drew Lock replacing Sam Darnold, who has 1,478 passing yards, 10 touchdowns and nine interceptions. Lock has completed 71.1% of his passes for 597 yards, five touchdowns and no interceptions. Las Vegas averages 26.4 points, but rookie Fernando Mendoza has completed just six of eight passes for 48 yards.
The Seattle Seahawks will be without Darnold and guard Quenton Nelson, while Leonard Williams missed Thursday's practice and Lock was limited with elbow and oblique issues. Las Vegas has fewer concerns, with Thomas Booker IV and Trey Zuhn III listed as questionable. The game is indoors at Allegiant Stadium, so weather will not affect play.
Seahawks vs Raiders Moneyline Pick
The Seattle Seahawks moneyline at -298 with DraftKings is the pick. Seattle allows 18.0 points per game and has recorded 21 sacks and eight interceptions, giving its defense an edge against rookie Fernando Mendoza.
Despite the expensive price, Seattle has the stronger defense and more experienced quarterback. Las Vegas averages just 71.3 rushing yards per game, making it harder to support Mendoza. These NFL predictions favor Seattle to win on the road.
Pick: Seattle Seahawks ML (-298 at DraftKings).
Against the Spread Pick
Take the Seattle Seahawks -6.5 at -112 with DraftKings. Seattle has the defensive numbers to create separation, especially against a Las Vegas offense averaging just 71.3 rushing yards per game. The Raiders will need Mendoza to handle more of the offensive workload, which presents a difficult challenge against a defense with 21 sacks and eight interceptions.
The 6.5-point spread requires Seattle to win by at least seven points. The Seahawks average 30:59 in time of possession per game, ranking 10th, while Las Vegas ranks 30th at 28:33. That difference points to more opportunities for Seattle to control the clock and limit the Raiders' possessions.
Pick: Seattle Seahawks -6.5 (-112 at DraftKings).
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Seahawks vs Raiders Game Total Pick
Take the Under 40.5 at -108 with DraftKings. Seattle's defense allows only 18.0 points per game, while Las Vegas will rely on Mendoza, who has completed six of eight passes for 48 yards in limited action. The rookie's lack of starting experience creates a difficult situation against a Seattle defense that has already produced 21 sacks and eight interceptions.
The Raiders average 26.4 points per game, but their league-worst rushing attack produces just 71.3 yards per game. Seattle's offense also averages only 22.4 points, creating another reason to expect a controlled game rather than a high-scoring contest. The quarterback changes add further uncertainty to the offensive production on both sides. This statistical analysis supports the Under as the strongest total selection and one of the clearest NFL Picks for Week 10.
Pick: Under 40.5 (-108 at DraftKings).
How to Watch Seahawks vs Raiders and Game Info
- Location: Allegiant Stadium, Las Vegas, NV.
- Date: Sunday, November 15, 2026
- Kickoff: 4:05 p.m. ET
- TV: CBS
- Seattle Seahawks starting quarterback: Drew Lock (TBD, 597 yards, 5-0 TD-INT).
- Las Vegas Raiders starting quarterback: Fernando Mendoza (TBD, 48 yards, TBD TD-INT).
- Weather forecast: Indoors, no weather factor.
Final Takeaways
The Seahawks have the stronger defensive matchup against a Las Vegas team preparing to start a rookie quarterback with only eight NFL pass attempts. The Seahawks are the moneyline pick at -298 and the spread selection at -6.5, while the Under 40.5 is the preferred total. These NFL predictions are based on Seattle's defensive production, the Raiders' weak rushing attack and Mendoza's limited experience. Bettors should prioritize Seattle's defensive advantage when weighing these three Expert betting tips for NFL games.
Check the latest odds and line movement for Seattle Seahawks vs Las Vegas Raiders at betting.net. All odds as of 4:24 a.m. ET on November 13, 2026. Odds sourced from DraftKings.