Bills Vs Jets: Betting Picks and Odds for NFL Week 10 Matchup
David Genge Published 12/11/2026
The Buffalo Bills are 8.5-point road favorites against the New York Jets on Sunday, November 15, at MetLife Stadium. DraftKings lists Buffalo at -520 on the moneyline, while the game total has climbed from 46.5 to 50.5 points. The Bills lead the NFL with 32 points per game, but their short week after Monday night's road game against Minnesota adds a scheduling concern to these NFL Picks.
Buffalo enters this divisional matchup with a significant offensive advantage. The Jets have struggled to produce consistent scoring, averaging just 20.2 points per game. These NFL predictions favor the Bills to win, but the spread and rising total deserve separate consideration.
Bills vs Jets Game Preview
The Buffalo Bills enters at 7-1, while New York is 2-7. Josh Allen has 2,027 passing yards, 12 touchdowns and six interceptions, plus nine rushing touchdowns. Geno Smith has 2,078 yards, 12 touchdowns and three interceptions, but the Jets average just 309.9 yards per game compared with Buffalo's 386.4. This statistical analysis of NFL teams highlights Buffalo's offensive advantage.
Both teams have injury concerns. Buffalo lists Dion Dawkins, Spencer Brown, Connor McGovern, Christian Benford and Greg Gaines on its injury report, while Dalton Kincaid was limited. Garrett Wilson is questionable with a concussion for New York, alongside Joseph Ossai, Trevin Wallace and Harrison Phillips. Buffalo also faces a short week after Monday night's road game. Sunday's forecast calls for clear skies, 43°F temperatures and 9 mph winds.
Bills vs Jets Moneyline Pick
Take the Buffalo Bills moneyline at -520 with DraftKings. Buffalo's league-leading 32 points per game and 386.4 yards per game give Allen's offense a significant advantage. The Jets average just 20.2 points and rank 25th in scoring, making it difficult for them to match Buffalo's offensive production.
The -520 price requires a $520 wager to earn $100 in profit. That is an expensive moneyline, but Buffalo's 7-1 record and offensive consistency support its position as the stronger team. Smith's 12 touchdowns and three interceptions give New York a capable quarterback, but the Jets have not produced enough yards to match the Bills. My NFL predictions favor Buffalo to secure the road win.
Pick: Buffalo Bills ML (-520 at DraftKings).
Against the Spread Pick
Take the Buffalo Bills -8.5 at DraftKings. Buffalo averages 32 points per game, an 11.8-point advantage over New York's 20.2. The Bills also produce 76.5 more yards per game, giving them more opportunities to sustain drives and create scoring chances throughout the afternoon.
The Bills -8.5 requires a win by at least nine points. The Bills' fifth-ranked time of possession (31:48) gives them an edge over the Jets (30:01). These NFL team performances favor the Bills to cover.
Pick: Buffalo Bills -8.5 (odds not provided at DraftKings).
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Bills vs Jets Game Total Pick
Take the Over 50.5 at DraftKings. The total has increased four points from its opening number of 46.5, reflecting expectations for more scoring. Buffalo's 32 points per game provide a strong foundation for the Over, especially against a New York team that has allowed the Bills to hold a substantial offensive advantage in the supplied statistics.
Allen has 12 passing touchdowns and nine rushing scores, while Smith has 12 touchdown passes and three interceptions. Wilson leads the Jets with 527 receiving yards and three touchdowns, but his questionable status is a concern. The Statistical analysis of NFL teams supports the Over based on Buffalo's scoring production.
Pick: Over 50.5 (odds not provided at DraftKings).
How to Watch Bills vs Jets and Game Info
- Location: MetLife Stadium, East Rutherford, NJ.
- Date: Sunday, November 15, 2026
- Kickoff: 1:00 p.m. ET
- TV: CBS
- Buffalo Bills starting quarterback: Josh Allen (7-1, 2,027 yards, 12-6 TD-INT).
- New York Jets starting quarterback: Geno Smith (2-7, 2,078 yards, 12-3 TD-INT).
- Weather forecast: 43°F, clear skies, wind at 9 mph.
Final Takeaways
The Bills has the stronger offense and a significant scoring advantage against a Jets team averaging only 20.2 points per game. The Bills are the moneyline selection at -520, while Buffalo -8.5 is the preferred spread despite the short-week concern. The Over 50.5 is also the pick, with Allen's passing and rushing production providing multiple scoring options. These NFL Picks favor Buffalo to control the matchup and deliver a strong offensive performance.
Odds sourced from DraftKings, as reported by NBC Sports. Check the latest odds and line movement for Buffalo Bills vs New York Jets at betting.net before placing your bets.