Commanders at Cowboys Predictions, Odds and Betting Picks
The Dallas Cowboys are 3.5-point home favorites over the Washington Commanders at FanDuel, with the moneyline at -215 and the total at 50.5. The strongest angle is a high-scoring game, with Dallas' defense coming off a 28-point performance allowed against the New York Giants and Washington bringing Jayden Daniels into another NFC East road game.
These teams both enter at 0-1 after losing close division games in Week 1. This guide breaks down the NFL Picks for the moneyline, spread and total, with the Statistical analysis of NFL teams focused on the matchup rather than broad season trends.
Commanders vs Cowboys Game Preview
Washington lost 24-22 to Philadelphia after failing on a late two-point attempt, while Dallas fell 28-20 to the Giants. Daniels finished Week 1 with 164 passing yards, 2 touchdowns and no interceptions in the supplied team data, while Dak Prescott posted 175 passing yards, 2 touchdowns and 1 interception. Washington also produced 295 yards and held the ball for 33:20, compared with Dallas' 244 yards and 23:20 of possession.
The injury report gives Washington more concern heading into Sunday. Frankie Luvu and Chig Okonkwo missed practice with groin and hamstring injuries, while Javon Kinlaw was added with a back issue. Dallas has its own defensive absences, with DeMarvion Overshown dealing with a hamstring injury and Malik Hooker listed with a forearm issue. The game will be played indoors at AT&T Stadium, removing wind and rain from the equation.
Commanders vs Cowboys Moneyline Pick
Take the Dallas Cowboys moneyline at -215 at FanDuel. Dallas has home-field advantage and faces a Washington defense that allowed 24 points to Philadelphia, while Prescott already showed red-zone production with 2 touchdown passes in Week 1.
The price is steep, but the matchup gives Dallas enough offensive firepower to justify laying the number. CeeDee Lamb caught 5 passes for 44 yards and a touchdown last week, while Javonte Williams scored twice, once rushing and once receiving. These factors make Dallas the moneyline side for these NFL Picks.
Pick: Cowboys ML (-215 at FanDuel).
Against the Spread Pick
Take the Washington Commanders +3.5 at -105 at FanDuel. The key number is 3, so getting Washington above that number matters in a division game where the teams lost their openers by only 2 and 8 points.
Washington also held a possession advantage of 33:20 to 23:20 in Week 1 and gained 295 total yards compared with Dallas' 244. Daniels added 45 rushing yards, giving Washington another way to stay within one score even if Dallas controls the passing matchup. That margin profile supports the Commanders against the spread even with Dallas favored to win.
For bettors building NFL predictions, the spread is a different question from the moneyline. Dallas can win at home while Washington still covers, especially with a 3.5-point cushion in an NFC East matchup.
Pick: Commanders +3.5 (-105 at FanDuel).
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Commanders vs Cowboys Game Total Pick
Take the Over 50.5 at -115 at FanDuel. The Cowboys have played two straight games with at least 48 combined points. The Over has also hit in each of Dallas' last 7 games, according to FOX Sports' matchup data.
The matchup also has the right offensive conditions for points. Washington averaged 295 yards in Week 1 and Dallas averaged 244, while both quarterbacks threw 2 touchdown passes. With the game inside AT&T Stadium, weather will not slow the passing game, which strengthens the Over case in these NFL predictions.
Pick: Over 50.5 (-115 at FanDuel).
How to Watch Washington Commanders vs Dallas Cowboys and Game Info
- Location: AT&T Stadium, Arlington, TX
- Date: Sunday, September 20, 2026
- Kickoff: 4:25 p.m. ET
- TV: FOX
- Washington Commanders starting quarterback: Jayden Daniels (0-1, 164 yards, 2-0).
- Dallas Cowboys starting quarterback: Dak Prescott (0-1, 175 yards, 2-1).
- Weather forecast: Indoors, no weather factor.
Final Takeaways
The main betting angle is to expect Dallas to win while Washington keeps the game within a field goal. The NFL Picks are Cowboys ML at -215, Commanders +3.5 at -105 and Over 50.5 at -115, with all odds from FanDuel.
Check the latest odds and line movement for Washington Commanders vs Dallas Cowboys at betting.net before placing your bets. All odds as of 4:10 AM ET on September 18, 2026. Odds sourced from FanDuel.