Vikings at Bears Predictions, Odds and Betting Picks
The Chicago Bears are 5.5-point home favorites against the Minnesota Vikings, with the biggest betting question centered on Minnesota's quarterback situation. Kyler Murray remains in concussion protocol, while Carson Wentz is expected to start after throwing 3 touchdown passes in relief during Minnesota's 39-22 Week 1 win.
Chicago enters Sunday after scoring 59 points against Carolina, while Caleb Williams threw for 269 yards and 2 touchdowns. That offensive output has pushed the Bears into a strong home favorite role, but Minnesota's fourth-quarter comeback and Wentz's efficient relief performance make this a tougher matchup than the spread suggests. These are the key factors behind our NFL Picks and NFL predictions for Week 2.
Vikings vs Bears Game Preview
Minnesota is 1-0 after rallying from a 22-10 deficit against Green Bay and scoring 29 unanswered points in the final stretch. Wentz completed 12 of 19 passes for 133 yards and 3 touchdowns, while Justin Jefferson caught 8 passes for 92 yards and 2 scores. Chicago also opened 1-0 after beating Carolina 59-37, with Williams throwing for 269 yards and 2 touchdowns and D'Andre Swift rushing for 124 yards.
The quarterback situation is the main lineup issue. Murray is listed as questionable with a concussion, and Wentz is expected to make his 100th career start if Murray cannot clear the protocol. Chicago has Williams confirmed as its starter, while Ozzy Trapilo and Xavier Woods are among the Bears listed as questionable. Jordan Mason is also questionable for Minnesota with a thumb injury.
Vikings vs Bears Moneyline Pick
Take the Chicago Bears moneyline at -235 at FanDuel. Chicago has the more stable quarterback situation with Williams confirmed, and the second-year quarterback enters after producing 269 passing yards and 2 touchdowns in Week 1. The Bears also scored 59 points and produced 552 total yards against Carolina, giving this offense a major statistical edge entering its home opener.
The -235 price is steep, but Chicago is the safer NFL Picks moneyline play. Wentz threw 3 TDs in Week 1, but Chicago forced 3 turnovers.
Pick: Bears ML (-235 at FanDuel).
Against the Spread Pick
Take the Minnesota Vikings +5.5 at -110 at FanDuel. The 5.5-point number gives Minnesota room to lose by one score while still cashing, and the Vikings already showed they can stay aggressive late after scoring 29 unanswered points against Green Bay. Wentz also posted a 123.5 passer rating in relief, which reduces the backdoor risk created by the quarterback change.
Chicago scored 59 points but allowed 37 to Carolina in Week 1. Justin Jefferson had 92 yards and 2 TDs, giving Minnesota enough offense to stay within 5.5 points. These NFL predictions favor Chicago to win, but Minnesota to cover.
Pick: Vikings +5.5 (-110 at FanDuel).
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Vikings vs Bears Game Total Pick
Take the Over 49.5 at -110 at FanDuel. Chicago scored 59 points in Week 1, while Minnesota scored 39, giving the teams a combined 98 points in their openers. The Bears also allowed 37 points to Carolina, while Minnesota's defense gave up 22 points to Green Bay before shutting the Packers out in the fourth quarter.
The matchup also features two quarterbacks who showed they can create points quickly. Williams produced 334 all-purpose yards and 4 total touchdowns against Carolina, while Wentz threw 3 touchdowns after entering the Minnesota game early. The strongest Expert betting tips for NFL games point toward another high-scoring NFC North matchup, especially with the total sitting below the combined Week 1 output of both teams.
Pick: Over 49.5 (-110 at FanDuel).
How to Watch Vikings vs Bears and Game Info
- Location: Soldier Field, Chicago, IL
- Date: Sunday, September 20, 2026
- Kickoff: 1:00 p.m. ET
- TV: FOX
- Minnesota Vikings starting quarterback: Carson Wentz (TBD, 133 yards, 3-0).
- Chicago Bears starting quarterback: Caleb Williams (TBD, 269 yards, 2-0).
- Weather forecast: 66°F, cloudy with a 15% to 20% chance of light rain, wind out of the northeast at 12 to 14 mph.
Final Takeaways
The quarterback situation makes Chicago the better moneyline side, but 5.5 points is enough room to take Minnesota against the spread. The NFL Picks are Bears moneyline, Vikings +5.5, and Over 49.5, with the total getting the strongest support from the 59 and 39 points these teams scored in Week 1. The NFL predictions also point to a competitive game despite Chicago's home-field advantage.
All odds as of 1:00 a.m. ET on September 15, 2026. Odds sourced from FanDuel. Check the latest odds and line movement for Minnesota Vikings vs Chicago Bears at betting.net before placing your bets.