Astros at Yankees Predictions, Odds and Betting Picks
David Genge Published 25/08/2026
The New York Yankees are the clear moneyline favorite at -149 against the Houston Astros at Yankee Stadium, with DraftKings listing Houston at +123. At those American odds, a $100 USD stake on New York would return $67.11 in profit, while a $100 USD stake on Houston would return $123 in profit. New York enters the opener 74-56 and has won six of its last seven games, while Houston sits at 65-66 and has gone 5-9 since early August.
Astros vs Yankees Game Preview
The Yankees bring a 74-56 record into the series opener and have won six of their last seven games. New York has also dealt with major rotation losses, with Max Fried on the 15-day IL, Ryan Weathers on the 15-day IL and Clarke Schmidt on the 60-day IL. Aaron Judge remains on the 60-day IL, while Cody Bellinger was activated August 23 after recovering from a hamstring strain.
Yankees vs. Astros Game Highlights (4/26/26) | MLB Highlights
Houston is 65-66 and 5-9 since early August. Jeremy Peña avoided the IL, while Mike Burrows, Carlos Correa and Brice Matthews remain sidelined with injuries. Ethan Pecko (0-0, 4.91 ERA) starts for Houston against Will Warren (8-6, 4.43 ERA). First pitch is 7:05 p.m. ET at Yankee Stadium, with clear skies, temperatures near 76°F to 78°F and 9 mph winds.
Moneyline Pick
The Yankees ML is the side. New York is -149 at DraftKings, which means a $100 USD stake would return $67.11 in profit, while Warren brings an 8-6 record and 122 strikeouts into a matchup against Pecko, who has a 4.91 ERA and four strikeouts.
The Yankees' 74-56 record and six wins in their last seven games add to the case for the home favorite. Houston's 5-9 stretch since early August gives New York the stronger recent form entering this matchup.
Pick: Yankees ML (-149 at DraftKings).
Run Line Pick
The Yankees -1.5 is the run line side. DraftKings lists New York at +144, while Houston is +1.5 at -175. A $100 USD stake on the Yankees at +144 would return $144 in profit if New York wins by at least two runs.
The price makes the Yankees a more aggressive play than the moneyline, but Warren's 4.43 ERA and 122 strikeouts give New York a stronger starting-pitching profile than Houston's Pecko, who owns a 4.91 ERA.
Pick: Yankees -1.5 (+144 at DraftKings).
Best Player Prop
- Will Warren strikeouts Over 5.5 (TBD at DraftKings). Warren has 122 strikeouts this season and averages a stronger strikeout profile than Pecko, who has only four strikeouts listed in the supplied starting-pitcher data. The Yankees right-hander also enters with an 8-6 record and 4.43 ERA.
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Game Total Pick
The Under 9 is the total side. DraftKings lists the Under 9 at -115 and the Over 9 at -105. At -115, a $100 USD stake on the Under would return $86.96 in profit if the total finishes below nine runs.
Warren enters with a 4.43 ERA, while Pecko owns a 4.91 ERA, giving both offenses a path to production but leaving the total at a relatively modest nine runs. The weather also provides stable conditions, with clear skies, temperatures around 76°F to 78°F, and a 9 mph west/northwest wind.
Pick: Under 9 (-115 at DraftKings).
Best Trades for Astros vs Yankees
Prediction-market prices give New York a 58¢ share price on Polymarket compared with 43¢ for Houston. Each share is denominated in U.S. dollars and can pay $1 USD if the selected outcome resolves as the winner. The strongest trade angles center on the Yankees' home edge, the standard 1.5-run spread and a first-inning scoring market priced above 50%.
- Astros vs. Yankees game winner: NO on Astros at 43¢ ($0.43 USD) on Polymarket. The Yankees are priced at 58¢ ($0.58 USD) to win, compared with 43¢ ($0.43 USD) for Houston, and New York enters with a 74-56 record and six wins in its last seven games.
- Astros +1.5: YES at 61¢ ($0.61 USD) on Polymarket. Houston's +1.5 share price is 61¢ ($0.61 USD), compared with 40¢ ($0.40 USD) for the Yankees -1.5. The market gives the Astros a stronger probability of staying within one run even though New York is favored to win outright.
- Run in the first inning: YES at 54¢ ($0.54 USD) on Polymarket. The YES price sits above the 50¢ mark, while Pecko brings a 4.91 ERA into Yankee Stadium. The Yankees also face a pitcher with only four listed strikeouts, creating an early opportunity for New York's lineup to pressure Houston.
How to Watch Astros vs Yankees and Game Info
- Location: Yankee Stadium, Bronx, NY
- Date: Tuesday, August 25, 2026
- First pitch: 7:05 p.m. ET
- TV: Yankees - YES; Astros - Space City Home Network.
- Astros starting pitcher: Ethan Pecko (0-0, 4.91 ERA).
- Yankees starting pitcher: Will Warren (8-6, 4.43 ERA).
- Weather forecast: 76°F to 78°F, fair and clear, wind from the west/northwest at 9 mph.
Final Takeaways
The Yankees have the clearest edge in this matchup because Warren's 8-6 record, 122 strikeouts, and a 4.43 ERA give New York the stronger starting-pitching profile. The Yankees are also 74-56 and have won six of their last seven, while Houston sits at 65-66 after going 5-9 since early August. The moneyline is the safest side, while the -1.5 run line offers a larger return at +144, which would produce $144 in profit on a $100 USD stake. The Under 9 also fits the matchup at a nine-run total with Warren starting for New York.
Check the latest odds and line movement for Astros vs Yankees at betting.net before placing your bets. All odds as of 7:05 p.m. ET on August 24, 2026. Odds sourced from DraftKings.